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File:A-Quantitative-Comparison-of-Human-HT-1080-Fibrosarcoma-Cells-and-Primary-Human-Dermal-Fibroblasts-pone.0081689.s017.ogv

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English: Dynamics of expanding and contracting bleb-like leading pseudopodia and corresponding movement of the cell body for an HT-1080 fibrosarcoma cell migrating in synthetic ECM. Time-lapse images (60 sec / frame) for an HT-1080 fibrosarcoma cell migrating in synthetic ECM (40 mg/mL 20,000 MW 8-arm PEG-NB, 50% MMP-degradable crosslinking density, 500 μM CRGDS). Semi-spherical bleb-like bulges form at the leading edge as the cell body cortically contracts (e.g., 16:00-28:00). The rear of the cell moves forward as the bleb-like feature contracts (e.g., 29:00-36:00). The same HT-1080 is also illustrated in Figure S6U. Time shown in Min:Sec. Scale bar = 25 μm.
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Source Movie S6 from Schwartz M, Rogers R, Singh S, Lee J, Loveland S, Koepsel J, Witze E, Montanez-Sauri S, Sung K, Tokuda E, Sharma Y, Everhart L, Nguyen E, Zaman M, Beebe D, Ahn N, Murphy W, Anseth K (2013). "A Quantitative Comparison of Human HT-1080 Fibrosarcoma Cells and Primary Human Dermal Fibroblasts Identifies a 3D Migration Mechanism with Properties Unique to the Transformed Phenotype". PLOS ONE. DOI:10.1371/journal.pone.0081689. PMID 24349113. PMC: 3857815.
Author Schwartz M, Rogers R, Singh S, Lee J, Loveland S, Koepsel J, Witze E, Montanez-Sauri S, Sung K, Tokuda E, Sharma Y, Everhart L, Nguyen E, Zaman M, Beebe D, Ahn N, Murphy W, Anseth K
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Date/TimeThumbnailDimensionsUserComment
current11:56, 22 March 20175.2 s, 92 × 59 (28 KB)Revent (talk | contribs)attempt to fix transcodes
05:09, 20 December 20135.2 s, 92 × 59 (15 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 240P 15 kbps Completed 02:12, 25 February 2026 1.0 s
WebM 360P 17 kbps Completed 01:54, 25 February 2026 1.0 s
QuickTime 144p (MJPEG) 121 kbps Completed 02:20, 25 February 2026 1.0 s

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