File:A-Quantitative-Comparison-of-Human-HT-1080-Fibrosarcoma-Cells-and-Primary-Human-Dermal-Fibroblasts-pone.0081689.s017.ogv
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[edit]| DescriptionA-Quantitative-Comparison-of-Human-HT-1080-Fibrosarcoma-Cells-and-Primary-Human-Dermal-Fibroblasts-pone.0081689.s017.ogv |
English: Dynamics of expanding and contracting bleb-like leading pseudopodia and corresponding movement of the cell body for an HT-1080 fibrosarcoma cell migrating in synthetic ECM. Time-lapse images (60 sec / frame) for an HT-1080 fibrosarcoma cell migrating in synthetic ECM (40 mg/mL 20,000 MW 8-arm PEG-NB, 50% MMP-degradable crosslinking density, 500 μM CRGDS). Semi-spherical bleb-like bulges form at the leading edge as the cell body cortically contracts (e.g., 16:00-28:00). The rear of the cell moves forward as the bleb-like feature contracts (e.g., 29:00-36:00). The same HT-1080 is also illustrated in Figure S6U. Time shown in Min:Sec. Scale bar = 25 μm. |
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| Source | Movie S6 from Schwartz M, Rogers R, Singh S, Lee J, Loveland S, Koepsel J, Witze E, Montanez-Sauri S, Sung K, Tokuda E, Sharma Y, Everhart L, Nguyen E, Zaman M, Beebe D, Ahn N, Murphy W, Anseth K (2013). "A Quantitative Comparison of Human HT-1080 Fibrosarcoma Cells and Primary Human Dermal Fibroblasts Identifies a 3D Migration Mechanism with Properties Unique to the Transformed Phenotype". PLOS ONE. DOI:10.1371/journal.pone.0081689. PMID 24349113. PMC: 3857815. | ||
| Author | Schwartz M, Rogers R, Singh S, Lee J, Loveland S, Koepsel J, Witze E, Montanez-Sauri S, Sung K, Tokuda E, Sharma Y, Everhart L, Nguyen E, Zaman M, Beebe D, Ahn N, Murphy W, Anseth K | ||
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This file is licensed under the Creative Commons Attribution 3.0 Unported license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 11:56, 22 March 2017 | 5.2 s, 92 × 59 (28 KB) | Revent (talk | contribs) | attempt to fix transcodes | |
| 05:09, 20 December 2013 | 5.2 s, 92 × 59 (15 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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